Malignancies induce a general immune response. The tumor micro‑environment consists of a variety of immune cells, such as:
Image from The Johanna Joyce Lab, Memorial Sloan Kettering Cancer Center
Myloid cells are a certain type of immune cell which emanate from stem cells in the bone marrow and travel to the site of the tumor.
Cancer cells impede the normal development of these myeloid cells and subvert their usual function.
Once corrupted by the cancer these cells engage in immune‑suppressive activities, and become known as Myeloid Derived Suppressor Cells (MDSCs).
Image from OncLive, Myeloid Cell Subtype Attracts Growing Interest as Immune System Target